We focus on using different structural biology and biophysical methods to solve problems related to nervous system development and disease. While the main focus is on the molecules involved in the assembly of the myelin sheath, our scientific interests are broad. In addition to structural neurobiology, we enjoy membrane-binding proteins, intrinsically disordered molecules, X-rays and neutrons, and ultrahigh-resolution X-ray crystallography of macromolecules – to name but a few.
Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin. Nicolas Snaidero, Caroline Velte, Matti Myllykoski, Arne Raasakka, Alexander Ignatev, Hauke B. Werner, Michelle S. Erwig, Wiebke Möbius, Petri Kursula, Klaus-Armin Nave, Mikael Simons
Cell Reports, Volume 18, Issue 2, p314–323, 10 January 2017